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About 20 years ago, the Beta-2 andrenoceptor became legendary virtually overnight when bodybuilders began to notice the support it had on developing lean muscle and burning bodyfat...
Bigger, Stronger AND Leaner? Ok, Keep Talking...
In short, this receptor, when activated, may increase cAMP, which activates Akt signalling, which results in decreased muscle catabolism by decreasing expression of various muscle specific ubiquitin protein ligases (e.g., atrogin-1/MAFbx), which are thought to be responsible for muscle protein degradation...
Furthermore, working through cAMP and non-cAMP mediated mechanisms, may ultimately result in increased activation of mammalian target of rapamycin (mTOR) signalling...
In a nutshell, it may help prevent muscle from breaking down, while also supporting muscle size.. If this weren't enough, by also increasing cAMP in fat tissue, Hormone Sensitive Lipase (HSL) may be activated, which stimulates lipolysis and may support a reduction of fat mass!
Spillover - Avoid At All Costs!
You see, your body not only has Beta-2 receptors, it also has additional closely-related receptors that most compounds in this class have \spillover\ towards - meaning they activate the Beta-2 receptor"""